For the vaccination of healthy cattle and sheep against diseases caused by Clostridium chauvoei, Cl. septicum, Cl. novyi Type B, Cl. haemolyticum (known elsewhere as Cl. novyi Type D), Cl. tetani and Cl. perfringens Types C and D.
Although Clostridium perfringens Type B is not considered a significant problem in the U.S.A., immunity may be provided against the beta and epsilon toxins elaborated by Cl. perfringens Type B. The immunity is derived from the combination of Type C (beta) and Type D (epsilon) fractions.
Cattle dosage: Inject 5 mL subcutaneously or intramuscularly, repeated in 6 weeks. Revaccinate annually with 5 mL prior to periods of extreme risk or parturition. For animals subject to reexposure to Cl. novyi Type B and Cl. haemolyticum repeat the dose every 5 to 6 months. For Cl. perfringens Types B, C and D, revaccinate two weeks prior to parturition, introduction to lush pastures or finishing programs. Calves vaccinated under 3 months of age should be revaccinated at weaning or 4 to 6 months of age.
Sheep dosage: Inject 5 mL subcutaneously followed by a 2 mL dose in 6 weeks. Revaccinate annually with 2 mL prior to periods of extreme risk or parturition. For Cl. novyi and Cl. haemolyticum, revaccinate every 5 to 6 months. Vaccination should be scheduled so that pregnant ewes receive their second vaccination or annual booster 2 to 6 weeks before lambing commences in the flock. Lambs should be given their primary course beginning at 10 to 12 weeks of age.
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